Table 1 Current clinical trials using stem cell-based therapies for Alzheimer’s disease (AD) and Parkinson’s disease (PD)
NCT Number | Study design | Stem cell type | Status | Estimated completion date | Disease |
|---|---|---|---|---|---|
NCT05667649 | Phase I | Autologous adipose derived MSC | Recruiting | March, 2025 | AD |
NCT04684602 | Phase I/II | Allogenic amniotic and umbilical cord tissue-derived MSC | Recruiting | December 09, 2030 | AD |
NCT04482413 | Phase IIb | Autologous adipose tissue-derived MSC | Not yet recruiting | December 20, 2024 | AD |
NCT03899298 | Phase I | Allogenic amniotic and umbilical cord tissue-derived MSC | Not yet recruiting | March 20, 2029 | AD |
NCT03724136 | N/A | Autologous BMSC | Enrolling by invitation | October, 2025 | AD |
NCT02899091 | Phase I/IIa | Allogenic placenta-derived MSC | Active, not recruiting | December, 2024 | AD |
NCT02833792 | Phase IIa | Allogenic human MSC | Recruiting | December 31, 2024 | AD |
NCT02795052 | N/A | Autologous BMSC | Recruiting | July 31, 2026 | AD |
NCT06482268 | Phase I/II | Allogenic iPSC-derived dopaminergic progenitor cells | Recruiting | May, 2028 | PD |
NCT06344026 | Phase I/IIa | Autologous iPSC-derived dopaminergic progenitor cells | Enrolling by invitation | April 30, 2030 | PD |
NCT06167681 | Phase I/II | Allogenic iPSC-derived dopaminergic progenitor cells | Recruiting | July, 2029 | PD |
NCT06145711 | N/A | Autologous iPSC-derived dopaminergic progenitor cells | Not yet recruiting | December 22, 2025 | PD |
NCT06141317 | Phase I/IIa | Allogenic adipose-derived MSC | Active, not recruiting | November 01, 2024 | PD |
NCT05901818 | Phase I | Autologous iPSC-derived dopaminergic progenitor cells | Recruiting | December 31, 2026 | PD |
NCT05887466 | Phase I/II | Allogenic ESC-derived dopamine progenitor cells | Active, not recruiting | February 07, 2026 | PD |
NCT05691114 | Phase I | Allogenic human amniotic epithelial MSC | Recruiting | February, 2026 | PD |
NCT05635409 | Phase I | Allogenic ESC-derived dopaminergic neurons | Recruiting | June, 2027 | PD |
NCT05152394 | Phase I | Allogenic umbilical cord-derived MSC | Not yet recruiting | January, 2026 | PD |
NCT05094011 | Phase I | Autologous adipose derived MSC | Not yet recruiting | July 31, 2026 | PD |
NCT04995081 | Phase II | Allogenic adipose-derived MSC | Recruiting | January 15, 2026 | PD |
NCT02795052 | N/A | Autologous BMSC | Recruiting | July 31, 2026 | PD |