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Fig. 4 | Translational Neurodegeneration

Fig. 4

From: N-terminus α-synuclein detection reveals new and more diverse aggregate morphologies in multiple system atrophy and Parkinson’s disease

Fig. 4

Comparison of total individual α-synuclein epitope immunolabelling in PD and MSA. Quantification of total N-terminus (yellow), pS129 (magenta), and C-terminus (cyan) epitope immunolabelling in (a) the hippocampus, medulla, and substantia nigra of PD and MSA cases, (b) the PD entorhinal cortex and olfactory bulb, and (c) the MSA cerebellum and inferior olivary nucleus. Boxplot colours correspond to colours of N-terminus (yellow), pS129 (magenta), and C-terminus (cyan) immunolabelling in representative images. White diamond = mean; crossbar = median; boxplots display interquartile range, and error bars indicate SD. ***P < 0.001, **P < 0.01, *P < 0.05

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