Table 1 Summary of case statistics (Mean ± SD) for human brain tissue used in this study (see Supplementary materials for further information)
MSA | PD | Neurologically normal | |
|---|---|---|---|
n | 10 (MSA-C, n = 5; MSA-P, n = 5) | 10 | 5 |
Disease duration (years) | 10.1 ± 5.1 | 17.1 ± 6.6 | – |
Age (years) | 67.7 ± 8.5 | 74.9 ± 5.3 | 81.8 ± 11.6 |
PMD (hours) | 24.6 ± 11.6 | 12.3 ± 7.1 | 26.2 ± 7 |
Average ABC Score [43] (maximum = 3) | A 0.5 ± 0.2 B 0.4 ± 0.2 C 0 | A 1.4 ± 1.2 B 0.6 ± 0.7 C 0.8 ± 0.8 | A 0.7 ± 0.3 B 1.0 ± 0.6 C 0 |
Braak Lewy Pathology Stage [10] (maximum = 6) | 0 | 4.9 ± 0.8 | 0 |
MSA Grade [44] (maximum = 3) | SND 2.1 ± 0.3 OPCA 1.3 ± 0.3 | 0 | 0 |